Renal Amyloidosis Associated With 5 Novel Variants in the Fibrinogen A Alpha Chain Protein

Renal Amyloidosis Associated With 5 Novel Variants in the Fibrinogen A Alpha Chain Protein

Fibrinogen A alpha chain amyloidosis is an autosomal dominant disease associated with mutations in the fibrinogen A alpha chain (FGA) gene, and it is the most common cause of hereditary renal amyloidosis in the UK. Patients typically present with kidney impairment and progress to end-stage renal dis...

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Bibliographic Details
Main Authors: Dorota Rowczenio, Maria Stensland, Gustavo A. de Souza, Erik H. Strøm, Janet A. Gilbertson, Graham Taylor, Nigel Rendell, Shane Minogue, Yvonne A. Efebera, Helen J. Lachmann, Ashutosh D. Wechalekar, Philip N. Hawkins, Ketil R. Heimdal, Kristian Selvig, Inger K. Lægreid, Nathalie Demoulin, Selda Aydin, Julian D. Gillmore, Tale N. Wien
Format: Article
Language:English
Published: Elsevier 2017-05-01
Series:Kidney International Reports
Subjects:
anti-GBM glomerulonephritis
end-stage renal disease (ESRD)
fibrinogen A alpha chain
hereditary renal amyloidosis
mass spectrometry-based proteomics
Online Access:http://www.sciencedirect.com/science/article/pii/S246802491630170X

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http://www.sciencedirect.com/science/article/pii/S246802491630170X

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