Cryo-EM Structures of Two Bacteriophage Portal Proteins Provide Insights for Antimicrobial Phage Engineering
Widespread antibiotic resistance has returned attention to bacteriophages as a means of managing bacterial pathogenesis. Synthetic biology approaches to engineer phages have demonstrated genomic editing to broaden natural host ranges, or to optimise microbicidal action. Gram positive pathogens cause...
Main Authors: | Abid Javed, Hugo Villanueva, Shadikejiang Shataer, Sara Vasciaveo, Renos Savva, Elena V. Orlova |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-12-01
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Series: | Viruses |
Subjects: | |
Online Access: | https://www.mdpi.com/1999-4915/13/12/2532 |
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