A Simple, Accurate and Cost-Effective Capillary Electrophoresis Test with Computational Methods to Aid in Universal Microsatellite Instability Testing

A Simple, Accurate and Cost-Effective Capillary Electrophoresis Test with Computational Methods to Aid in Universal Microsatellite Instability Testing

Background: Microsatellite instability (MSI) testing is important for the classification of Lynch syndrome, as a prognostic marker and as a guide for adjuvant chemotherapy in colorectal cancer (CRC). The gold standard for determining MSI status has traditionally been fluorescent multiplex polymerase...

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Bibliographic Details
Main Authors: James Wei Tatt Toh, Puneet Singh, Venkata A. A. S. K. Tangirala, Alex Limmer, Kevin J. Spring
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cells
Subjects:
microsatellite instability
MSI
mismatch repair deficiency
MMRD
Lynch syndrome
capillary electrophoresis
Online Access:https://www.mdpi.com/2073-4409/10/6/1401

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https://www.mdpi.com/2073-4409/10/6/1401

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