Molecular mechanism of cargo recognition and handover by the mammalian signal recognition particle

Molecular mechanism of cargo recognition and handover by the mammalian signal recognition particle

Summary: Co-translational protein targeting to membranes by the signal recognition particle (SRP) is a universally conserved pathway from bacteria to humans. In mammals, SRP and its receptor (SR) have many additional RNA features and protein components compared to the bacterial system, which were re...

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Bibliographic Details
Main Authors: Ahmad Jomaa, Simon Eitzinger, Zikun Zhu, Sowmya Chandrasekar, Kan Kobayashi, Shu-ou Shan, Nenad Ban
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Cell Reports
Subjects:
signal recognition particle
cryoelectron microscopy
co-translational protein targeting
GTPases
ribosome nascent chain complex
transmembrane domain
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721007269

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http://www.sciencedirect.com/science/article/pii/S2211124721007269

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