Transcranial focused ultrasound-induced blood‒brain barrier opening in mice without shaving hairs

Abstract Acoustic coupling through hairs remains a challenge to performing transcranial-focused ultrasound procedures. Here, we demonstrated that this challenge could be addressed by using oil as the coupling medium, leveraging oil's high affinity to hairs due to their inherent hydrophobicity....

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Bibliographic Details
Main Authors: Lu Xu, Yan Gong, Chih-Yen Chien, Eric Leuthardt, Hong Chen
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-40598-4