Optimizing Nanopore Sequencing for Rapid Detection of Microbial Species and Antimicrobial Resistance in Patients at Risk of Surgical Site Infections

Optimizing Nanopore Sequencing for Rapid Detection of Microbial Species and Antimicrobial Resistance in Patients at Risk of Surgical Site Infections

ABSTRACT Surgical site infections (SSI) are a significant burden to patients and health care systems. We evaluated the use of Nanopore sequencing (NS) to rapidly detect microbial species and antimicrobial resistance (AMR) genes present in intraoperative bile aspirates. Bile aspirates from 42 patient...

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Bibliographic Details
Main Authors: Emma Whittle, Jennifer A. Yonkus, Patricio Jeraldo, Roberto Alva-Ruiz, Heidi Nelson, Michael L. Kendrick, Thomas E. Grys, Robin Patel, Mark J. Truty, Nicholas Chia
Format: Article
Language:English
Published: American Society for Microbiology 2022-02-01
Series:mSphere
Subjects:
antimicrobial resistance
microbial detection
nanopore sequencing
surgical site infection
Online Access:https://journals.asm.org/doi/10.1128/msphere.00964-21

Internet

https://journals.asm.org/doi/10.1128/msphere.00964-21

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