Proteolysis of the human DNA polymerase delta smallest subunit p12 by μ-calpain in calcium-triggered apoptotic HeLa cells.
Degradation of p12 subunit of human DNA polymerase delta (Pol δ) that results in an interconversion between Pol δ4 and Pol δ3 forms plays a significant role in response to replication stress or genotoxic agents triggered DNA damage. Also, the p12 is readily degraded by human calpain in vitro. Howeve...
| Hoofdauteurs: | , , , , , , , , , , |
|---|---|
| Formaat: | Artikel |
| Taal: | English |
| Gepubliceerd in: |
Public Library of Science (PLoS)
2014-01-01
|
| Reeks: | PLoS ONE |
| Online toegang: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0093642&type=printable |