Sustained release local anesthetics for pain management: relevance and formulation approaches

Sustained release local anesthetics for pain management: relevance and formulation approaches

This review attempted to ascertain the rationale for the formulation of sustained-release local anesthetics and summarize the various formulation approaches designed to date to achieve sustained and localized local analgesic effects. The incidence of pain, which is the concern of patients as well as...

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Bibliographic Details
Main Authors: Melese Getachew, Hana Tesfaye, Wubetu Yihunie, Tesfahun Ayenew, Sintayehu Alemu, Ephrem Mebratu Dagnew, Yalemgeta Biyazin, Dehnnet Abebe, Natanim Degefu, Abtie Abebaw
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Pain Research
Subjects:
chronic pain
formulation approaches
liposomal formulations
lipid nanoparticles
local anesthetics
localized analgesia
Online Access:https://www.frontiersin.org/articles/10.3389/fpain.2024.1383461/full

Internet

https://www.frontiersin.org/articles/10.3389/fpain.2024.1383461/full

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