Mitogen-activated protein kinase eight polymorphisms are associated with immune responsiveness to HBV vaccinations in infants of HBsAg(+)/HBeAg(−) mothers

Mitogen-activated protein kinase eight polymorphisms are associated with immune responsiveness to HBV vaccinations in infants of HBsAg(+)/HBeAg(−) mothers

Abstract Background Infants born to hepatitis B surface antigen (HBsAg) positive mothers are at a higher risk for Hepatitis B virus (HBV) infection. Host genetic background plays an important role in determining the strength of immune response to vaccination. We conducted this study to investigate t...

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Bibliographic Details
Main Authors: Meng Zhuo Cao, Yan Hua Wu, Si Min Wen, Yu Chen Pan, Chong Wang, Fei Kong, Chuan Wang, Jun Qi Niu, Jie Li, Jing Jiang
Format: Article
Language:English
Published: BMC 2018-06-01
Series:BMC Infectious Diseases
Subjects:
Hepatitis B vaccination
MAPK8
TNF
Mother-to-infant transmission
Low response
Online Access:http://link.springer.com/article/10.1186/s12879-018-3166-x

Internet

http://link.springer.com/article/10.1186/s12879-018-3166-x

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