Mutation of NIMA-related kinase 1 (NEK1) leads to chromosome instability

Mutation of NIMA-related kinase 1 (NEK1) leads to chromosome instability

<p>Abstract</p> <p>Background</p> <p>NEK1, the first mammalian ortholog of the fungal protein kinase never-in-mitosis A (NIMA), is involved early in the DNA damage sensing/repair pathway. A defect in DNA repair in NEK1-deficient cells is suggested by persistence of DNA...

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Bibliographic Details
Main Authors: Hansel Donna E, Edwards Robert A, Wei Randy L, Polci Rosaria, Pena Michelle, Chiang Huai-Chin, Chen Chi-Fen, Chen Yumay, Chen Phang-Lang, Riley Daniel J
Format: Article
Language:English
Published: BMC 2011-01-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/10/1/5

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http://www.molecular-cancer.com/content/10/1/5

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