A randomized controlled non-inferiority trial of placebo versus macrolide antibiotics for Mycoplasma pneumoniae infection in children with community-acquired pneumonia: trial protocol for the MYTHIC Study

A randomized controlled non-inferiority trial of placebo versus macrolide antibiotics for Mycoplasma pneumoniae infection in children with community-acquired pneumonia: trial protocol for the MYTHIC Study

Abstract Background Mycoplasma pneumoniae is a major cause of community-acquired pneumonia (CAP) in school-aged children. Macrolides are the first-line treatment for this infection. However, it is unclear whether macrolides are effective in treating M. pneumoniae CAP, mainly due to limitations in mi...

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Bibliographic Details
Main Authors: Patrick M. Meyer Sauteur, Michelle Seiler, Romy Tilen, Ester Osuna, Margarete von Wantoch, Semjon Sidorov, Christoph Aebi, Philipp Agyeman, Florence Barbey, Julia A. Bielicki, Ludivine Coulon, Beate Deubzer, Alex Donas, Ulrich Heininger, Kristina Keitel, Henrik Köhler, Lisa Kottanattu, Roger Lauener, Anita Niederer-Loher, Klara M. Posfay-Barbe, Maren Tomaske, Noémie Wagner, Petra Zimmermann, Franziska Zucol, Stefanie von Felten, Christoph Berger
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Trials
Subjects:
Anti-inflammatory
Antimicrobial
Atypical pneumonia
Azithromycin
Carriage
Colonization
Online Access:https://doi.org/10.1186/s13063-024-08438-6

Internet

https://doi.org/10.1186/s13063-024-08438-6

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