RBMS3-induced circHECTD1 encoded a novel protein to suppress the vasculogenic mimicry formation in glioblastoma multiforme

Abstract Glioblastoma multiforme (GBM) is a highly vascularized malignant cancer of the central nervous system, and the presence of vasculogenic mimicry (VM) severely limits the effectiveness of anti-vascular therapy. In this study, we identified downregulated circHECTD1, which acted as a key VM-sup...

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Bibliographic Details
Main Authors: Xuelei Ruan, Yunhui Liu, Ping Wang, Libo Liu, Teng Ma, Yixue Xue, Weiwei Dong, Yubo Zhao, Tiange E, Hongda Lin, Di Wang, Chunqing Yang, Jian Song, Jiate Liu, Meiqi Deng, Ping An, Yang Lin, Jin Yang, Zheng Cui, Yaming Cao, Xiaobai Liu
Format: Article
Language:English
Published: Nature Publishing Group 2023-11-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06269-y