Doxazosin Treatment Attenuates Carbon Tetrachloride-Induced Liver Fibrosis in Hamsters through a Decrease in Transforming Growth Factor β Secretion

Background/AimsThe development of therapeutic strategies for the treatment of cirrhosis has become an important focus for basic and clinical researchers. Adrenergic receptor antagonists have been evaluated as antifibrotic drugs in rodent models of carbon tetrachloride (CCl4)-induced cirrhosis. The a...

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Bibliographic Details
Format: Article
Language:English
Published: Gastroenterology Council for Gut and Liver 2016-01-01
Series:Gut and Liver
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Online Access:http://gutnliver.org/journal/view.html?doi=10.5009/gnl14459