Investigation of the impact of nonsynonymous mutations on thyroid peroxidase dimer.

Investigation of the impact of nonsynonymous mutations on thyroid peroxidase dimer.

Congenital hypothyroidism is one of the most common preventable endocrine disorders associated with thyroid dysgenesis or dyshormonogenesis. Thyroid peroxidase (TPO) gene defect is mainly responsible for dyshormonogenesis; a defect in the thyroid hormone biosynthesis pathway. In Bangladesh, there is...

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Main Authors: Mst Noorjahan Begum, Rumana Mahtarin, Sinthyia Ahmed, Imrul Shahriar, Shekh Rezwan Hossain, Md Waseque Mia, Syed Saleheen Qadri, Firdausi Qadri, Kaiissar Mannoor, Sharif Akhteruzzaman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0291386

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https://doi.org/10.1371/journal.pone.0291386

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