Modulation of MAPK and NF-κB Signaling Pathways by Antioxidant Therapy in Skeletal Muscle of Heart Failure Rats

Modulation of MAPK and NF-κB Signaling Pathways by Antioxidant Therapy in Skeletal Muscle of Heart Failure Rats

Background/Aims: Although increased oxidative stress plays a role in heart failure (HF)-induced skeletal myopathy, signaling pathways involved in muscle changes and the role of antioxidant agents have been poorly addressed. We evaluated the effects of N-acetylcysteine (NAC) on intracellular signalin...

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Bibliographic Details
Main Authors: Paula F. Martinez, Camila Bonomo, Daniele M. Guizoni, Silvio A. Oliveira Junior, Ricardo L. Damatto, Marcelo D.M. Cezar, Aline R.R. Lima, Luana U. Pagan, Fabio R. Seiva, Renata T. Bueno, Denise C. Fernandes, Francisco R. Laurindo, Leonardo A.M. Zornoff, Katashi Okoshi, Marina P. Okoshi
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-06-01
Series:Cellular Physiology and Biochemistry
Subjects:
Oxidative stress
Intracellular signaling
Myocardial infarction
Cardiac failure
Skeletal muscle
Myopathy
Online Access:http://www.karger.com/Article/FullText/445631

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http://www.karger.com/Article/FullText/445631

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