The challenge of translating ischemic conditioning from animal models to humans: the role of comorbidities

Following a period of ischemia (local restriction of blood supply to a tissue), the restoration of blood supply to the affected area causes significant tissue damage. This is known as ischemia-reperfusion injury (IRI) and is a central pathological mechanism contributing to many common disease states...

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Bibliographic Details
Main Authors: Kieran McCafferty, Suzanne Forbes, Christoph Thiemermann, Muhammad M. Yaqoob
Format: Article
Language:English
Published: The Company of Biologists 2014-12-01
Series:Disease Models & Mechanisms
Subjects:
Online Access:http://dmm.biologists.org/content/7/12/1321