The challenge of translating ischemic conditioning from animal models to humans: the role of comorbidities
Following a period of ischemia (local restriction of blood supply to a tissue), the restoration of blood supply to the affected area causes significant tissue damage. This is known as ischemia-reperfusion injury (IRI) and is a central pathological mechanism contributing to many common disease states...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2014-12-01
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Series: | Disease Models & Mechanisms |
Subjects: | |
Online Access: | http://dmm.biologists.org/content/7/12/1321 |