Aliskiren and valsartan in combination is a promising therapy for hypertensive renal injury in rats
Neither ACEI nor ARBs completely repress the RAAS. Aliskiren is a newer agent that inhibits renin. However, it increases the biosynthesis and secretion of renin and prorenin, that might induce renal tissue damage. This study was conducted to investigate the renoprotective effects of aliskiren and va...
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Format: | Article |
Language: | English |
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Taylor & Francis Group
2018-08-01
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Series: | Clinical and Experimental Hypertension |
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Online Access: | http://dx.doi.org/10.1080/10641963.2017.1407333 |