Differentiation of Human Induced Pluripotent Stem Cells from Patients with Severe COPD into Functional Airway Epithelium

Differentiation of Human Induced Pluripotent Stem Cells from Patients with Severe COPD into Functional Airway Epithelium

Background: Chronic Obstructive Pulmonary Disease (COPD), a major cause of mortality and disability, is a complex disease with heterogeneous and ill-understood biological mechanisms. Human induced pluripotent stem cells (hiPSCs) are a promising tool to model human disease, including the impact of ge...

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Bibliographic Details
Main Authors: Engi Ahmed, Mathieu Fieldes, Chloé Bourguignon, Joffrey Mianné, Aurélie Petit, Myriam Jory, Chantal Cazevieille, Hassan Boukhaddaoui, James P. Garnett, Christophe Hirtz, Gladys Massiera, Isabelle Vachier, Said Assou, Arnaud Bourdin, John De Vos
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Cells
Subjects:
airway epithelium
chronic obstructive pulmonary disease
disease modeling
human induced pluripotent stem cells
Online Access:https://www.mdpi.com/2073-4409/11/15/2422

Internet

https://www.mdpi.com/2073-4409/11/15/2422

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