A single-cell view on host immune transcriptional response to in vivo BCG-induced trained immunity

A single-cell view on host immune transcriptional response to in vivo BCG-induced trained immunity

Summary: Bacillus Calmette-Guérin (BCG) vaccination is a prototype model for the study of trained immunity (TI) in humans, and results in a more effective response of innate immune cells upon stimulation with heterologous stimuli. Here, we investigate the heterogeneity of TI induction by single-cell...

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Bibliographic Details
Main Authors: Wenchao Li, Simone J.C.F.M. Moorlag, Valerie A.C.M. Koeken, Rutger J. Röring, L. Charlotte J. de Bree, Vera P. Mourits, Manoj K. Gupta, Bowen Zhang, Jianbo Fu, Zhenhua Zhang, Inge Grondman, Krista E. van Meijgaarden, Liang Zhou, Ahmed Alaswad, Leo A.B. Joosten, Reinout van Crevel, Cheng-Jian Xu, Mihai G. Netea, Yang Li
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Cell Reports
Subjects:
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723004989

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http://www.sciencedirect.com/science/article/pii/S2211124723004989

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