Preclinical evaluation of a candidate naked plasmid DNA vaccine against SARS-CoV-2

Abstract New generation plasmid DNA vaccines may be a safe, fast and simple emergency vaccine platform for preparedness against emerging viral pathogens. Applying platform optimization strategies, we tested the pre-clinical immunogenicity and protective effect of a candidate DNA plasmid vaccine spec...

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Bibliographic Details
Main Authors: Ria Lassaunière, Charlotta Polacek, Gregers J. Gram, Anders Frische, Jeanette Linnea Tingstedt, Maren Krüger, Brigitte G. Dorner, Anthony Cook, Renita Brown, Tatyana Orekov, Tammy Putmon-Taylor, Tracey-Ann Campbell, Jack Greenhouse, Laurent Pessaint, Hanne Andersen, Mark G. Lewis, Anders Fomsgaard
Format: Article
Language:English
Published: Nature Portfolio 2021-12-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-021-00419-z