Evaluation of lung protection of Sanghuangporus sanghuang through TLR4/NF-κB/MAPK, keap1/Nrf2/HO-1, CaMKK/AMPK/Sirt1, and TGF-β/SMAD3 signaling pathways mediating apoptosis and autophagy

Evaluation of lung protection of Sanghuangporus sanghuang through TLR4/NF-κB/MAPK, keap1/Nrf2/HO-1, CaMKK/AMPK/Sirt1, and TGF-β/SMAD3 signaling pathways mediating apoptosis and autophagy

Idiopathic pulmonary fibrosis (IPF) is a type of interstitial pneumonia characterized by chronic and progressive fibrosis with an unknown etiology. Previous pharmacological studies have shown that Sanghuangporus sanghuang possesses various beneficial properties including immunomodulatory, hepatoprot...

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Bibliographic Details
Main Authors: Liang-Hsuan Chien, Jeng-Shyan Deng, Wen-Ping Jiang, Ya-Ni Chou, Jaung-Geng Lin, Guan-Jhong Huang
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Sanghuangporus sanghuang
Idiopathic pulmonary fibrosis
Anti-inflammation
Oxidative stress
Apoptosis
Autophagy
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223008715

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http://www.sciencedirect.com/science/article/pii/S0753332223008715

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