Increases in the risk of cognitive impairment and alterations of cerebral β-amyloid metabolism in mouse model of heart failure.

Epidemiological and clinico-pathological studies indicate a causal relationship between heart disease and Alzheimer's disease (AD). To learn whether heart disease causes an onset of AD, mice with myocardial infarction (MI) and congestive heart failure (HF) were used to test neuropsychiatric and...

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Bibliographic Details
Main Authors: Xiaoqi Hong, Liping Bu, Yi Wang, Jing Xu, Jian Wu, Yufang Huang, Jie Liu, Haiyun Suo, Lumeng Yang, Yuncen Shi, Yi Lou, Zhengliang Sun, Guoqi Zhu, Thomas Behnisch, Mei Yu, Jianguo Jia, Wangxi Hai, Hongping Meng, Sheng Liang, Fang Huang, Yunzeng Zou, Junbo Ge
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3667825?pdf=render