Proline provides site-specific flexibility for in vivo collagen

Proline provides site-specific flexibility for in vivo collagen

Abstract Fibrillar collagens have mechanical and biological roles, providing tissues with both tensile strength and cell binding sites which allow molecular interactions with cell-surface receptors such as integrins. A key question is: how do collagens allow tissue flexibility whilst maintaining wel...

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Bibliographic Details
Main Authors: Wing Ying Chow, Chris J. Forman, Dominique Bihan, Anna M. Puszkarska, Rakesh Rajan, David G. Reid, David A. Slatter, Lucy J. Colwell, David J. Wales, Richard W. Farndale, Melinda J. Duer
Format: Article
Language:English
Published: Nature Portfolio 2018-09-01
Series:Scientific Reports
Subjects:
13Cγ Chemical Shifts
Proline Ring
Collagen Model Peptides
Collagen Triple Helix
Backbone Dihedrals
Online Access:https://doi.org/10.1038/s41598-018-31937-x

Internet

https://doi.org/10.1038/s41598-018-31937-x

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