Proline provides site-specific flexibility for in vivo collagen
Abstract Fibrillar collagens have mechanical and biological roles, providing tissues with both tensile strength and cell binding sites which allow molecular interactions with cell-surface receptors such as integrins. A key question is: how do collagens allow tissue flexibility whilst maintaining wel...
Main Authors: | Wing Ying Chow, Chris J. Forman, Dominique Bihan, Anna M. Puszkarska, Rakesh Rajan, David G. Reid, David A. Slatter, Lucy J. Colwell, David J. Wales, Richard W. Farndale, Melinda J. Duer |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2018-09-01
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Series: | Scientific Reports |
Subjects: | |
Online Access: | https://doi.org/10.1038/s41598-018-31937-x |
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