RRx-001 Increases Erythrocyte Preferential Adhesion to the Tumor Vasculature

RRx-001 Increases Erythrocyte Preferential Adhesion to the Tumor Vasculature

Red blood cells (RBCs) serve a variety of functions beyond mere oxygen transport both in health and pathology. Notably, RRx-001, a minimally toxic pleiotropic anticancer agent with macrophage activating and vascular normalization properties currently in Phase III trials, induces modification to RBCs...

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Bibliographic Details
Main Authors: Vinay P. Jani, Robert Asaro, Bryan Oronsky, Pedro Cabrales
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
RRx-001
tumor microenvironment
RBC adhesion
shear stress
Online Access:https://www.mdpi.com/1422-0067/22/9/4713

Internet

https://www.mdpi.com/1422-0067/22/9/4713

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