Changes in Dickkopf-1 (DKK1) and Sclerostin following a Loading Dose of Vitamin D2 (300,000 IU)

Background. Vitamin D is important for bone health, although high loading doses have been associated with an increase in fracture risk. The mechanisms remain uncertain. Aim. We hypothesize that supraphysiological concentrations of 1,25 (OH)2 vitamin D may inhibit formation by increasing the producti...

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Bibliographic Details
Main Authors: A. Sankaralingam, R. Roplekar, C. Turner, R. N. Dalton, G. Hampson
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Journal of Osteoporosis
Online Access:http://dx.doi.org/10.1155/2014/682763