Linkage analysis using whole exome sequencing data implicates SLC17A1, SLC17A3, TATDN2 and TMEM131L in type 1 diabetes in Kuwaiti families

Linkage analysis using whole exome sequencing data implicates SLC17A1, SLC17A3, TATDN2 and TMEM131L in type 1 diabetes in Kuwaiti families

Abstract Type 1 diabetes (T1D) is characterized by the progressive destruction of pancreatic β-cells, leading to insulin deficiency and lifelong dependency on exogenous insulin. Higher estimates of heritability rates in monozygotic twins, followed by dizygotic twins and sib-pairs, indicate the role...

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Bibliographic Details
Main Authors: Prashantha Hebbar, Rasheeba Nizam, Sumi Elsa John, Dinu Antony, Mohammad Dashti, Arshad Channanath, Azza Shaltout, Hessa Al-Khandari, Heikki A. Koistinen, Jaakko Tuomilehto, Osama Alsmadi, Thangavel Alphonse Thanaraj, Fahd Al-Mulla
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-42255-2

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https://doi.org/10.1038/s41598-023-42255-2

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