Bacterial neuraminidase rescues influenza virus replication from inhibition by a neuraminidase inhibitor.

Influenza virus neuraminidase (NA) cleaves terminal sialic acid residues on oligosaccharide chains that are receptors for virus binding, thus playing an important role in the release of virions from infected cells to promote the spread of cell-to-cell infection. In addition, NA plays a role at the i...

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Bibliographic Details
Main Authors: Tomoko Nishikawa, Kazufumi Shimizu, Torahiko Tanaka, Kazumichi Kuroda, Tadatoshi Takayama, Tatsuo Yamamoto, Nobuhiro Hanada, Yoshiki Hamada
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3445474?pdf=render