Protein structure and folding pathway prediction based on remote homologs recognition using PAthreader

PAthreader generates templates of remote homologous structures to improve protein structure prediction by AlphaFold2 and predict folding pathways under the hypothesis that folding information is evolutionarily conserved in remote homologs.

Bibliographic Details
Main Authors: Kailong Zhao, Yuhao Xia, Fujin Zhang, Xiaogen Zhou, Stan Z. Li, Guijun Zhang
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-04605-8