A new DNA aptamer which binds to SARS-CoV-2 spike protein and reduces pro-inflammatory response

Abstract COVID-19 caused by SARS-CoV-2 spread rapidly around the world, endangering the health of people globally. The SARS-CoV-2 spike protein initiates entry into target cells by binding to human angiotensin-converting enzyme 2 (ACE2). In this study, we developed DNA aptamers that specifically bin...

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Bibliographic Details
Main Authors: Woong Kim, Eun Su Song, Song Ha Lee, Seung Ho Yang, Junhyung Cho, Seok-Jun Kim
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-024-58315-0