L-glutamine protects against enterohemorrhagic Escherichia coli infection by inhibiting bacterial virulence and enhancing host defense concurrently

L-glutamine protects against enterohemorrhagic Escherichia coli infection by inhibiting bacterial virulence and enhancing host defense concurrently

ABSTRACT Enterohemorrhagic Escherichia coli (EHEC) can colonize the gastrointestinal tract and cause bloody diarrhea in children. Previous studies showed that its pathogenesis could be mediated by metabolites from both the host and microbiota. L-Glutamine (Gln) was found to be depleted in intestinal...

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Bibliographic Details
Main Authors: Fang Fang, Yunxin Xue, Xuefang Xu, Dingli Fang, Weijia Liu, Ying Zhong, Jinping Han, Yunhe Li, Qian Tao, Rong Lu, Cong Ma, Arvind Kumar, Dai Wang
Format: Article
Language:English
Published: American Society for Microbiology 2023-12-01
Series:Microbiology Spectrum
Subjects:
enterohemorrhagic Escherichia coli
L-glutamine
nitrogen metabolism
type 3 secretion system
antivirulence
host defense
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00975-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.00975-23

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