EFFECT OF N-ACETYLCYSTEINE ON APOPTOSIS OF P19 CANCER CELLS DURING HYPOXIA

EFFECT OF N-ACETYLCYSTEINE ON APOPTOSIS OF P19 CANCER CELLS DURING HYPOXIA

Introduction. Hypoxia in tumor growth contributes to mitochondrial dysfunction and exacerbates oxidative stress in the immortalized cell. The objective of the study was to investigate the molecular mechanisms of the effects of N-acetylcysteine on redox regulation of tumor cell apoptosis under hypoxi...

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Bibliographic Details
Main Authors: O. L. Nosareva, D. S. Orlov, E. V. Shakhristova, E. A. Stepovaya, A. A. Sadykova
Format: Article
Language:Russian
Published: Russian Academy of Sciences, Tomsk National Research Medical Center 2020-07-01
Series:Сибирский онкологический журнал
Subjects:
tumor growth
apoptosis
oxidative stress
hypoxia
glutathione system
n-acetylcystein
Online Access:https://www.siboncoj.ru/jour/article/view/1493

Internet

https://www.siboncoj.ru/jour/article/view/1493

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