The PPAR-γ Agonist Pioglitazone Modulates Proliferation and Migration in HUVEC, HAOSMC and Human Arteriovenous Fistula-Derived Cells

The PPAR-γ Agonist Pioglitazone Modulates Proliferation and Migration in HUVEC, HAOSMC and Human Arteriovenous Fistula-Derived Cells

The failure of arteriovenous fistulas (AVFs) following intimal hyperplasia (IH) increases morbidity and mortality rates in patients undergoing hemodialysis for chronic kidney disease. The peroxisome-proliferator associated receptor (PPAR-γ) may be a therapeutic target in IH regulation. In the presen...

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Bibliographic Details
Main Authors: Carmen Ciavarella, Ilenia Motta, Francesco Vasuri, Teresa Palumbo, Anthony Paul Lisi, Alice Costa, Annalisa Astolfi, Sabrina Valente, Piera Versura, Eugenio F. Fornasiero, Raffaella Mauro, Mauro Gargiulo, Gianandrea Pasquinelli
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
intimal hyperplasia (IH)
arteriovenous fistula (AVF)
proliferation
migration
PPAR-γ
pioglitazone
Online Access:https://www.mdpi.com/1422-0067/24/5/4424

Internet

https://www.mdpi.com/1422-0067/24/5/4424

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