Vti1a/b support distinct aspects of TGN and cis-/medial Golgi organization

Abstract Retrograde trafficking towards the trans-Golgi network (TGN) is important for dense core vesicle (DCV) biogenesis. Here, we used Vti1a/b deficient neurons to study the impact of disturbed retrograde trafficking on Golgi organization and cargo sorting. In Vti1a/b deficient neurons, staining...

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Bibliographic Details
Main Authors: Danique M. van Bommel, Ruud F. Toonen, Matthijs Verhage
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-25331-x