Increased mitochondrial fusion allows the survival of older animals in diverse C. elegans longevity pathways
Mitochondria can undergo shape changes as a result of fusion and fission events. Here the authors describe how insulin signalling regulates mitochondrial fusion in C. elegans, and show that mitochondrial fusion is necessary, but not sufficient, for longevity of worms with mutations that increase lif...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2017-08-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-017-00274-4 |