Erythromycin Restores Osteoblast Differentiation and Osteogenesis Suppressed by <i>Porphyromonas gingivalis</i> Lipopolysaccharide

Erythromycin Restores Osteoblast Differentiation and Osteogenesis Suppressed by <i>Porphyromonas gingivalis</i> Lipopolysaccharide

The macrolide erythromycin (ERM) inhibits excessive neutrophil accumulation and bone resorption in inflammatory tissues. We previously reported that the expression of developmental endothelial locus-1 (DEL-1), an endogenous anti-inflammatory factor induced by ERM, is involved in ERM action. Furtherm...

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Bibliographic Details
Main Authors: Hikaru Tamura, Tomoki Maekawa, Hisanori Domon, Kridtapat Sirisereephap, Toshihito Isono, Satoru Hirayama, Takumi Hiyoshi, Karin Sasagawa, Fumio Takizawa, Takeyasu Maeda, Yutaka Terao, Koichi Tabeta
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Pharmaceuticals
Subjects:
macrolides
periodontitis
<i>Porphyromonas gingivalis</i> lipopolysaccharide
osteoblastogenesis
developmental endothelial locus-1
Online Access:https://www.mdpi.com/1424-8247/16/2/303

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https://www.mdpi.com/1424-8247/16/2/303

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