Selecting Closely-Linked SNPs Based on Local Epistatic Effects for Haplotype Construction Improves Power of Association Mapping

Selecting Closely-Linked SNPs Based on Local Epistatic Effects for Haplotype Construction Improves Power of Association Mapping

Genome-wide association studies (GWAS) have gained central importance for the identification of candidate loci underlying complex traits. Single nucleotide polymorphism (SNP) markers are mostly used as genetic variants for the analysis of genotype-phenotype associations in populations, but closely l...

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Bibliographic Details
Main Authors: Fang Liu, Renate H. Schmidt, Jochen C. Reif, Yong Jiang
Format: Article
Language:English
Published: Oxford University Press 2019-12-01
Series:G3: Genes, Genomes, Genetics
Subjects:
haplotype
epistasis
genome-wide association study
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.119.400451

Internet

http://g3journal.org/lookup/doi/10.1534/g3.119.400451

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