Identification of T Cell Receptors Targeting a Neoantigen Derived from Recurrently Mutated FGFR3

Immunotherapies, including immune checkpoint blockades, play a critically important role in cancer treatments. For immunotherapies, neoantigens, which are generated by somatic mutations in cancer cells, are thought to be good targets due to their tumor specificity. Because neoantigens are unique in...

Full description

Bibliographic Details
Main Authors: Tomohiro Tate, Saki Matsumoto, Kensaku Nemoto, Matthias Leisegang, Satoshi Nagayama, Kazutaka Obama, Yusuke Nakamura, Kazuma Kiyotani
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/15/4/1031