1,25-Dihydroxyvitamin D<sub>3</sub> Negatively Regulates the Inflammatory Response to Porcine Epidemic Diarrhea Virus Infection by Inhibiting NF-κB and JAK/STAT Signaling Pathway in IPEC-J2 Porcine Epithelial Cells

1,25-Dihydroxyvitamin D<sub>3</sub> Negatively Regulates the Inflammatory Response to Porcine Epidemic Diarrhea Virus Infection by Inhibiting NF-κB and JAK/STAT Signaling Pathway in IPEC-J2 Porcine Epithelial Cells

Porcine epidemic diarrhea virus (PEDV) infection causes watery diarrhea and vomiting in piglets. The pathogenesis of PEDV infection is related to intestinal inflammation. It is known that 1,25-dihydroxyvitamin D<sub>3</sub> (1,25(OH)<sub>2</sub>D<sub>3</sub>) has...

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Bibliographic Details
Main Authors: Jiwen Yang, Daiwen Chen, Gang Tian, Xiangbing Mao, Jun He, Ping Zheng, Jie Yu, Yuheng Luo, Junqiu Luo, Zhiqing Huang, Aimin Wu, Hui Yan, Bing Yu
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
1,25(OH)<sub>2</sub>D<sub>3</sub>
inflammation
PEDV
JAK/STAT signaling pathway
NF-κB
Online Access:https://www.mdpi.com/1422-0067/23/18/10603

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https://www.mdpi.com/1422-0067/23/18/10603

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