Clofazimine pharmacokinetics in HIV‐infected adults with diarrhea: Implications of diarrheal disease on absorption of orally administered therapeutics

Clofazimine pharmacokinetics in HIV‐infected adults with diarrhea: Implications of diarrheal disease on absorption of orally administered therapeutics

Abstract Oral drug absorption kinetics are usually established in populations with a properly functioning gastrointestinal tract. However, many diseases and therapeutics can alter gastrointestinal physiology and cause diarrhea. The extent of diarrhea‐associated impact on drug pharmacokinetics has no...

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Bibliographic Details
Main Authors: Cindy X. Zhang, Thomas M. Conrad, David Hermann, Melita A. Gordon, Eric Houpt, Pui‐Ying Iroh Tam, Khuzwayo C. Jere, Wilfred Nedi, Darwin J. Operario, Jacob Phulusa, Gerald V. Quinnan Jr, Leigh A. Sawyer, Lynn K. Barrett, Herbert Thole, Neema Toto, Wesley C. Van Voorhis, Samuel L. M. Arnold
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:CPT: Pharmacometrics & Systems Pharmacology
Online Access:https://doi.org/10.1002/psp4.13092

Internet

https://doi.org/10.1002/psp4.13092

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