The Na+, K+-ATPase β1 subunit regulates epithelial tight junctions via MRCKα

The Na+, K+-ATPase β1 subunit regulates epithelial tight junctions via MRCKα

An intact lung epithelial barrier is essential for lung homeostasis. The Na+, K+-ATPase (NKA), primarily serving as an ion transporter, also regulates epithelial barrier function via modulation of tight junctions. However, the underlying mechanism is not well understood. Here, we show that overexpre...

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Bibliographic Details
Main Authors: Haiqing Bai, Rui Zhou, Michael Barravecchia, Rosemary Norman, Alan Friedman, Deborah Yu, Xin Lin, Jennifer L. Young, David A. Dean
Format: Article
Language:English
Published: American Society for Clinical investigation 2021-02-01
Series:JCI Insight
Subjects:
Cell biology
Pulmonology
Online Access:https://doi.org/10.1172/jci.insight.134881

Internet

https://doi.org/10.1172/jci.insight.134881

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