The First Type III Domain of Fibronectin is Associated with the Expression of Cytokines within the Lung Tumor Microenvironment

<p>Recent studies have pointed to changes in tissue mechanics as a contributory element to the development of malignancies. Increased tissue rigidity is associated with the unfolding of the Type III domains of fibronectin within the extracellular matrix. The consequences of this unfolding on c...

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Bibliographic Details
Main Author: Mingzhe Zheng, David M. Jones, Carol Horzempa, Aparna Prasad, Paula J. McKeown-Longo
Format: Article
Language:English
Published: Ivyspring International Publisher 2011-01-01
Series:Journal of Cancer
Online Access:http://www.jcancer.org/v02p0478.htm