Inhibition of Hyperglycemia and Hyperlipidemia by Blocking Toll-like Receptor 4: Comparison of Wild-Type and Toll-like Receptor 4 Gene Knockout Mice on Obesity and Diabetes Modeling

Inhibition of Hyperglycemia and Hyperlipidemia by Blocking Toll-like Receptor 4: Comparison of Wild-Type and Toll-like Receptor 4 Gene Knockout Mice on Obesity and Diabetes Modeling

Innate immune receptor TLR4 plays an important role in glycolipid metabolism. The objective of this study is to investigate the inhibitory effects of blocking TLR4 on hyperglycemia and hyperlipidemia by comparing WT and TLR4<sup>−/−</sup> mice in obesity and diabetes modeling. The knocko...

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Bibliographic Details
Main Authors: Xingyu Zhao, Jiawei Zheng, Jing Wang, Bin Li, Wuyang Huang
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Biology
Subjects:
TLR4
glycolipid metabolism
obesity and diabetes modeling
knockout
Online Access:https://www.mdpi.com/2079-7737/13/1/63

Internet

https://www.mdpi.com/2079-7737/13/1/63

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