Myeloid Derived Suppressor Cells Expansion Persists After Early ART and May Affect CD4 T Cell Recovery

Myeloid Derived Suppressor Cells Expansion Persists After Early ART and May Affect CD4 T Cell Recovery

Myeloid-derived suppressor cells (MDSC) are expanded during HIV-1 infection and correlated with disease progression. MDSC expand in the early phase of primary infection depending on TRAIL level. In this study we evaluated the effect of ART on the frequency of MDSC in patients with primary HIV infect...

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Bibliographic Details
Main Authors: Chiara Agrati, Nicola Tumino, Veronica Bordoni, Carmela Pinnetti, Andrea Sabatini, Alessandra Amendola, Isabella Abbate, Patrizia Lorenzini, Annalisa Mondi, Rita Casetti, Eleonora Cimini, Germana Grassi, Andrea Antinori, Alessandra Sacchi
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Immunology
Subjects:
MDSC
HIV
early ART
early T cell progenitors
TRAIL
GM-CSF
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01886/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01886/full

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