Large scale sequence-based screen for recessive variants allows for identification and monitoring of rare deleterious variants in pigs.

Most deleterious variants are recessive and segregate at relatively low frequency. Therefore, high sample sizes are required to identify these variants. In this study we report a large-scale sequence based genome-wide association study (GWAS) in pigs, with a total of 120,000 Large White and 80,000 S...

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Bibliographic Details
Main Authors: Anne Boshove, Martijn F L Derks, Claudia A Sevillano, Marcos S Lopes, Maren van Son, Egbert F Knol, Bert Dibbits, Barbara Harlizius
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1011034&type=printable