Distinct genetic clusters in HIV-1 CRF01_AE-infected patients induced variable degrees of CD4+ T-cell loss

Distinct genetic clusters in HIV-1 CRF01_AE-infected patients induced variable degrees of CD4+ T-cell loss

ABSTRACT CRF01_AE strains have been shown to form multiple transmission clusters in China, and some clusters have disparate pathogenicity in Chinese men who have sex with men. This study focused on other CRF01_AE clusters prevalent in heterosexual populations. The CD4+ T-cell counts from both cross-...

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Bibliographic Details
Main Authors: Kang Li, Huanhuan Chen, Jianjun Li, Yi Feng, Shujia Liang, Abdur Rashid, Meiliang Liu, Sisi Li, Qingfei Chu, Yuhua Ruan, Hui Xing, Guanghua Lan, Wentao Qiao, Yiming Shao
Format: Article
Language:English
Published: American Society for Microbiology 2024-03-01
Series:mBio
Subjects:
HIV-1
genetic cluster
viral virulence
co-receptor tropism
CD4+ T-cell count
Online Access:https://journals.asm.org/doi/10.1128/mbio.03349-23

Internet

https://journals.asm.org/doi/10.1128/mbio.03349-23

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