Efficacy of metformin therapy in patients with cancer: a meta-analysis of 22 randomised controlled trials

Efficacy of metformin therapy in patients with cancer: a meta-analysis of 22 randomised controlled trials

Abstract Background To investigate whether metformin monotherapy or adjunctive therapy improves the prognosis in patients with any type of cancer compared to non-metformin users (age ≥18). Methods Databases (Medline, Embase, and the Cochrane Central Register of Controlled Trials) and clinical trial...

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Bibliographic Details
Main Authors: Jie Wen, Zhenjie Yi, Yuyao Chen, Jing Huang, Xueyi Mao, Liyang Zhang, Yu Zeng, Quan Cheng, Wenrui Ye, Zhixiong Liu, Fangkun Liu, Jingfang Liu
Format: Article
Language:English
Published: BMC 2022-10-01
Series:BMC Medicine
Subjects:
Metformin
Cancer
RCTs
Meta-analysis
Cancer-related mortality
Online Access:https://doi.org/10.1186/s12916-022-02599-4

Internet

https://doi.org/10.1186/s12916-022-02599-4

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