Induction, decay, and determinants of functional antibodies following vaccination with the RTS,S malaria vaccine in young children

Induction, decay, and determinants of functional antibodies following vaccination with the RTS,S malaria vaccine in young children

Abstract Background RTS,S is the first malaria vaccine recommended for implementation among young children at risk. However, vaccine efficacy is modest and short-lived. Antibodies play the major role in vaccine-induced immunity, but knowledge on the induction, decay, and determinants of antibody fun...

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Bibliographic Details
Main Authors: Gaoqian Feng, Liriye Kurtovic, Paul A. Agius, Elizabeth H. Aitken, Jahit Sacarlal, Bruce D. Wines, P. Mark Hogarth, Stephen J. Rogerson, Freya J. I. Fowkes, Carlota Dobaño, James G. Beeson
Format: Article
Language:English
Published: BMC 2022-08-01
Series:BMC Medicine
Subjects:
Malaria
Phagocytosis
Neutrophils
Monocytes
Vaccines
Children
Online Access:https://doi.org/10.1186/s12916-022-02466-2

Internet

https://doi.org/10.1186/s12916-022-02466-2

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