HIV-1 <i>Trans</i> Infection via TNTs Is Impeded by Targeting C5aR

Nonadjacent immune cells communicate through a complex network of tunneling nanotubes (TNTs). TNTs can be hijacked by HIV-1, allowing it to spread between connected cells. Dendritic cells (DCs) are among the first cells to encounter HIV-1 at mucosal sites, but they are usually efficiently infected o...

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Bibliographic Details
Main Authors: Giulia Bertacchi, Wilfried Posch, Doris Wilflingseder
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/12/2/313