Reprogramming Macrophage Polarization, Depleting ROS by Astaxanthin and Thioketal‐Containing Polymers Delivering Rapamycin for Osteoarthritis Treatment
Abstract Osteoarthritis (OA) is a chronic joint disease characterized by synovitis and joint cartilage destruction. The severity of OA is highly associated with the imbalance between M1 and M2 synovial macrophages. In this study, a novel strategy is designed to modulate macrophage polarization by re...
Main Authors: | Huiyun Li, Yusong Yuan, Lingpu Zhang, Chun Xu, Hailin Xu, Zhiwei Chen |
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Format: | Article |
Language: | English |
Published: |
Wiley
2024-03-01
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Series: | Advanced Science |
Subjects: | |
Online Access: | https://doi.org/10.1002/advs.202305363 |
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